MRI of bioregenerative approaches in cartilage repair: Differentiation of repair tissue after matrix-associated autologous chondrocyte transplantation using a hyaloronic acid-based or a collagen-based scaffold with advanced morphological scoring and biochemical T2 relaxation time mapping
نویسندگان
چکیده
G. H. Welsch, T. C. Mamisch, L. Zak, M. Blanke, A. Olk, S. Marlovits, and S. Trattnig MR Center, Department of Radiology, Medical University of Vienna, Vienna, Austria, Department of Trauma and Orthpaedic Surgery, University Hospital of Erlangen, Erlangen, Germany, Department of Orthopaedic Surgery, University of Basel, Basel, Switzerland, Center for Joints and Cartilage, Department of Trauma Surgery, Medical University of Vienna, Vienna, Austria
منابع مشابه
Morphological and biochemical (T2) MR evaluation and comparison of cartilage repair tissue of the patella and the medial femoral condyle
Introduction: In a recent survey on 25,124 knee arthroscopies, cartilage lesions were found most frequently within the patella (36%) and the medial femoral condyle (34%). However, there is a clear topographical difference in cartilage surface and cartilage thickness between these two anatomical sites. Furthermore, when looking at biochemical and biomechanical properties, this regional variation...
متن کاملQuantitative T2 mapping of matrix-associated autologous chondrocyte transplantation at 3 Tesla: an in vivo cross-sectional study.
OBJECTIVES To evaluate magnetic resonance (MR) T2 mapping for characterization of cartilage repair tissue following matrix-associated autologous cartilage transplantation (MACT). MATERIALS AND METHODS Fifteen patients were evaluated following MACT using a 3T MR scanner. Patients were categorized into 2 postoperative intervals: I: 3-13 months, II: 19-42 months. Mean T2 relaxation times calcula...
متن کاملMatrix-Associated and Autologous Chondrocyte Transplantation in the Ankle
BACKGROUND New matrix-associated autologous chondrocyte transplantation (MACT) techniques may facilitate the treatment of chondral defects in talar cartilage and provide good clinical outcome in the long term. The aim of this prospective case series was to monitor the clinical outcome after autologous chondrocyte transplantation (ACT) and MACT in the ankle to gain data on the mid-term efficacy ...
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INTRODUCTION: Autologous chondrocyte transplantation (ACT) is a routine technique to regenerate cartilage tissue in chondral lesions [1]. Instead of using periosteal patch, the method can be enhanced by seeding the cultureexpanded chondrocytes into a biodegradable 3-dimensional scaffold (matrix-associated ACT). These new generation ACT techniques lead to less surgical time, morbidity, and aboli...
متن کامل[Tissue engineering applications: cartilage lesions repair by the use of autologous chondrocytes].
Promising new therapies based on tissue engineering have been recently developed for cartilage repair. The association of biomaterials with autologous chondrocytes expanded in vitro can represent a useful tool to regenerate this tissue. The scaffolds utilised in such therapeutical applications should provide a pre-formed three-dimensional shape, prevent cells from floating out of the defect, ha...
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تاریخ انتشار 2009